{"id":1882,"date":"2024-10-10T14:24:50","date_gmt":"2024-10-10T06:24:50","guid":{"rendered":"https:\/\/www.niuniucard.com\/blog\/?p=1882"},"modified":"2024-10-10T14:26:10","modified_gmt":"2024-10-10T06:26:10","slug":"2024%e5%b9%b4%e8%af%ba%e8%b4%9d%e5%b0%94%e5%8c%96%e5%ad%a6%e5%a5%96%e6%8f%ad%e6%99%93%ef%bc%9aai-%e9%a2%84%e6%b5%8b%e8%9b%8b%e7%99%bd%e8%b4%a8%e7%bb%93%e6%9e%84","status":"publish","type":"post","link":"\/blog\/archives\/1882","title":{"rendered":"2024\u5e74\u8bfa\u8d1d\u5c14\u5316\u5b66\u5956\u63ed\u6653\uff1aAI \u9884\u6d4b\u86cb\u767d\u8d28\u7ed3\u6784"},"content":{"rendered":"\n

2024\u5e74\u8bfa\u5956\u5316\u5b66\u5956\u9881\u7ed9\u8d1d\u514b\u3001\u54c8\u8428\u6bd4\u65af\u7b49\u3002<\/p>\n\n\n\n

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10\u67089\u65e5\uff0c\u745e\u5178\u7687\u5bb6\u79d1\u5b66\u9662\u5ba3\u5e03\uff0c2024\u5e74\u8bfa\u8d1d\u5c14\u5316\u5b66\u5956\u5c06\u9881\u53d1\u7ed9\u5927\u536b\u00b7\u8d1d\u514b\uff08David Baker\uff09<\/strong>\uff0c\u53e6\u4e00\u534a\u6388\u4e88\u6770\u7c73\u65af\u00b7\u54c8\u8428\u6bd4\u65af\uff08Demis Hassabis\uff09<\/strong>\u548c\u7ea6\u7ff0\u00b7\u8a79\u73c0\uff08John M.Jumper\uff09<\/strong>\uff0c\u4ee5\u8868\u5f70\u4ed6\u4eec\u5bf9\u86cb\u767d\u8d28\u79d1\u5b66\u7684\u5f00\u521b\u6027\u8d21\u732e\u3002<\/p>\n\n\n\n

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\u4e09\u4eba\u5f00\u542f\u4e00\u4e2a\u65b0\u672a\u6765<\/strong><\/strong><\/h2>\n\n\n\n

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\u6b63\u662f\u8d1d\u514b\uff0c\u57282003\u5e74\u6210\u529f\u4ece\u5934\u8bbe\u8ba1\uff08De novo design\uff09\u4e86\u4e00\u79cd\u65b0\u7684\u86cb\u767d\u8d28\u3002<\/p>\n\n\n\n

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\u5927\u536b\u00b7\u8d1d\u514b\u56e2\u961f\u8bbe\u8ba1\u4e86\u4e00\u4e2a\u542b\u670993\u4e2a\u6c28\u57fa\u9178\u6b8b\u57fa\u7684\u03b1\/\u03b2\u86cb\u767d\uff0c\u5177\u6709\u5168\u65b0\u7684\u62d3\u6251\u7ed3\u6784\uff0c\u80fd\u591f\u81ea\u52a8\u6298\u53e0\u6210\u7403\u72b6\u5e76\u975e\u5e38\u7a33\u5b9a\u3002\u8fd9\u4e2a\u86cb\u767d\u88ab\u547d\u540d\u4e3aTop7\uff0c\u8fd9\u662f\u4eba\u7c7b\u7b2c\u4e00\u6b21\u83b7\u5f97\u4e86\u975e\u81ea\u7136\u754c\u6765\u6e90\u7684\u5168\u65b0\u86cb\u767d\u8d28\uff0c\u4ee3\u8868\u7740\u4eba\u7c7b\u5728\u4ece\u5934\u8bbe\u8ba1\u86cb\u767d\u9886\u57df\u8fc8\u51fa\u4e86\u4e00\u5927\u6b65\u3002David Baker\u4e5f\u56e0\u6b64\u88ab\u4e00\u4e9b\u5a92\u4f53\u79f0\u4e3a\u201c\u4e0a\u5e1d\u4e4b\u624b\u201d\u3002<\/p>\n\n\n\n

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2020\u5e7411\u670830\u65e5\uff0cAlphaFold2\u5728\u56fd\u9645\u86cb\u767d\u8d28\u7ed3\u6784\u9884\u6d4b\u7ade\u8d5b\uff08CASP\uff09\u4e2d\u4e00\u4e3e\u593a\u9b41\uff0c\u5176\u9884\u6d4b\u7684\u86cb\u767d\u8d28\u7ed3\u6784\u5df2\u8fbe\u5230\u539f\u5b50\u7cbe\u5ea6\uff0c\u53ef\u4e0e\u5b9e\u9a8c\u6d4b\u5f97\u7684\u7ed3\u6784\u76f8\u5ab2\u7f8e\u3002\u8981\u77e5\u9053\uff0c\u591a\u5e74\u6765\uff0c\u79d1\u5b66\u5bb6\u53ea\u80fd\u901a\u8fc7\u6838\u78c1\u5171\u632f\u3001X\u5c04\u7ebf\u548c\u51b7\u51bb\u7535\u955c\u6280\u672f\u6765\u786e\u5b9a\u86cb\u767d\u8d28\u7684\u7ed3\u6784\u3002\u4ed6\u4eec\u9700\u8981\u4e3a\u4e86\u4e00\u4e2a\u86cb\u767d\u8d28\u7ed3\u6784\u53cd\u590d\u8bd5\u9a8c\uff0c\u5176\u95f4\u82b1\u8d39\u4e86\u6570\u5e74\u65f6\u95f4\u548c\u5de8\u989d\u8d39\u7528\u30022005\u5e74\uff0c\u300a\u79d1\u5b66\u300b\u6742\u5fd7\u5728\u521b\u520a125\u5468\u5e74\u4e4b\u9645\u5c06\u9884\u6d4b\u86cb\u767d\u8d28\u7ed3\u6784\u5217\u4e3a125\u4e2a\u6700\u5177\u6311\u6218\u6027\u7684\u79d1\u5b66\u95ee\u9898\u4e4b\u4e00\u3002\u56e0\u6b64\uff0cAlphaFold\u7684\u8fd9\u6b21\u80dc\u5229\u88ab\u89c6\u4e3a\u89e3\u51b3\u4e8650\u5e74\u6765\u751f\u7269\u5b66\u9886\u57df\u7684\u4e00\u4e2a\u91cd\u5927\u6311\u6218\u3002<\/p>\n\n\n\n

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\u90fd\u662f\u5de5\u4f5c\u72c2<\/strong><\/strong><\/h2>\n\n\n\n

\u6210\u7acb\u4ec5\u4e00\u5e74\u7684AI\u5236\u836f\u516c\u53f8Xaira Therapeutics\uff0c\u57282023\u5e74\u5438\u5f15\u523010\u4ebf\u7f8e\u5143\u7684\u5355\u8f6e\u878d\u8d44\uff0c\u8fd9\u5bb6\u516c\u53f8\u7684\u8054\u5408\u521b\u59cb\u4eba\u6b63\u662f\u5927\u536b\u00b7\u8d1d\u514b\u3002\u4ed6\u4e5f\u662f\u7f8e\u56fd\u751f\u5316\u5b66\u5bb6\u3001\u534e\u76db\u987f\u5927\u5b66\u86cb\u767d\u8d28\u8bbe\u8ba1\u7814\u7a76\u6240\u6240\u957f\u3002<\/p>\n\n\n\n

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